Photo(s):

Document(s):

Trademarks:

L7 Loratadine intermediate

Generic Name:

8-Chloro-10, 11-dihydro-4-aza-5H-dibenzo (a, d) cycloheptan-5-one

Manufacturer:

Morepen

Quantity:

378 Kgs

Packaging:

Drums

LOT #:

Available upon request

CAS #:

31251-41-9

Appearance:

Slight yellow crystalline powder

Manufacturing date:

12/2024

Retest date:

11/2027

Details:

8-Chloro-10,11-dihydro-4-aza-5H-dibenzo[a,d]cycloheptan-5-one is a chlorinated tricyclic ketone intermediate used in the synthesis of loratadine and related antihistamine active pharmaceutical ingredients.

Applications:
- Pharmaceutical: Key intermediate in the manufacture of loratadine and structurally related antihistamine APIs.
- Chemical synthesis: Building block for tricyclic aza-dibenzocycloheptanone derivatives used in medicinal chemistry development.
- Research and development: Reference intermediate for process optimization, impurity profiling, and route development in API synthesis.